Spatial autocorrelation analysis tests the dependance of the values of a variable on the values of the same variable at other locations. So far, this method has been used in population genetics to study geographical patterns of gene sequences. The software here available computes autocorrelation statistics from samples of DNA data, either sequences or RFLPs, according to the paper by Bertorelle and Barbujani, 1995 (Genetics 140:811-819).

The package consists of two programs (executable files for PC), a description file (WinWord format) with all the information to run the programs, and 11 example files. All these files are zipped in the AIDA.ZIP file. Remember that the data files must be stored in a subdirectory called dati.

Click here to download AIDA.ZIP
Click here to read the documentation
 
 
 

ADMIX: Inferring Admixture Proportion from Molecular Data

The package Admix1_0 computes the relative contribution from two parental populations to a hybrid population by using the estimator mY described in Bertorelle & Excoffier, 1998 (Mol. Biol. Evol. 15: 1298-1311).
It also computes two other estimators of the admixture coefficient: mC (Chakraborty et al., 1992, Am. J. hum. Genet. 50: 145-155) and mR (Robert & Hiorns, 1965, Hum. Biol. 37: 38-43).
The main difference between mY and the other two estimators is that mY also takes into account the molecular distance between the different alleles (see Bertorelle & Excoffier for more details).

The package consists of an executable file (for PC), two example files and a readme text file with some instructions about the use of the program. These 4 files are compressed in the ADMIX1_0.ZIP file.

Click here to download ADMIX1_0.ZIP
Click here to read the documentation
 
 
 

DIVAGE: MLE of Population Divergence Times

This package can be used to compute the estimators of the divergence time between two populations proposed by Bertorelle & Rannala (PNAS, in press). These estimators are designed for the analysis of  frequencies of nonrecurrent rare mutations.

The package consists of two executable files (for PC), one example file and a readme.doc file (Word for Windows format) with some instruction about the use of the program. These 3 files are compressed in the DIVAGE..ZIP file.

Click here to download DIVAGE.ZIP
Click here to read the documentation